Toxicology Research

《毒理学研究》旨在发布卓越和创新的前沿研究，推动毒理学并具有国际影响力。文章应涵盖毒性反应的化学或生物方面以及所涉及的机制。该期刊的范围包括以下内容：纳米毒理学，强烈鼓励研究纳米材料和与人类健康直接相关的常见纳米材料的毒性反应的生化或分子机制。致癌性，包括致癌物的作用方式，遗传毒性和突变的研究毒性的生物标志物，包括对其鉴定，验证和利用的研究计算和预测毒理学，包括体外，体内和计算机毒性研究以及预测工具和模型的开发。鼓励考虑采用替代方法进行体内研究。系统毒理学，描述化学物质对特定器官或系统（例如，免疫，神经，生殖，呼吸）的毒理学影响的研究，包括纳入基因组学，代谢组学和蛋白质组学数据的研究风险评估，提供毒理学数据或信息的研究 - 例如危害识别，剂量反应评估风险评估或监管制定的风险暴露评估环境毒理学，如果对人类健康有更广泛的益处，鼓励报告生态系统内生物的毒理学数据。临床毒理学，有关毒理学研究的临床试验或药物应用的研究，包括转化毒理学，研究将临床应用的毒性反应的分子理解转化为临床应用。食品毒理学，与食品和营养有关的化学提取物的毒理学研究。涉及无特征提取物或其中食物仅具有有限或当地利益的研究应在其他地方提交。分析计量学，包括新分析方法和应用的研究

Toxicology Research aims to publish cutting edge research that is excellent and innovative, that drives toxicology and has international impact. Articles should cover chemical or biological aspects of the toxic response and the mechanisms involved.The journal''s scope includes the following.Nanotoxicology, studies on the biochemical or molecular mechanisms of toxic responses to nanomaterials and common nanomaterials which are of direct relevance to human health, are strongly encouraged. Carcinogenicity, including studies on mode of action of carcinogens, genotoxicity and mutationBiomarkers of toxicity, including studies on their identification, validation, and utilisationComputational and predictive toxicology, including in vitro, in vivo and in silico studies of toxicity and the development of predictive tools and models. Work considering alternative methods to in vivo studies is encouraged.Systems toxicology, studies that describe the toxicological effects of chemicals on specific organs or systems (for example, immune, nervous, reproductive, respiratory), including studies that incorporate genomic, metabonomic and proteomic dataRisk assessment, studies which provide toxicological data or information – such as hazard identification, dose-response assessmentExposure assessment for the development of risk assessments or regulationEnvironmental toxicology, studies reporting toxicology data for organisms within an ecosystem are encouraged if there is a wider benefit to human health.Clinical toxicology, studies relating to clinical trials or medicinal applications of toxicological research, including translational toxicology, Studies translating a molecular understanding of the toxic response to clinical application.Food toxicology, toxicological studies of chemical extracts related to food and nutrition. Studies that involve uncharacterised extracts or in which the food substance is only of limited or local interest should be submitted elsewhere.Analytical metrology, including studies of new analytical methods and applications