CardioRenal Medicine

《心肾医学》杂志探讨了肥胖和其他代谢异常促进心脏和肾脏疾病(心肾代谢综合征)发病和进展的机制。它提供了一个跨学科的平台，以推进研究和临床实践，集中在翻译问题。人们注意到一些代谢异常与心脏和慢性肾脏疾病聚集在一起，统称为心肾代谢综合征。此外，心脏的某些代谢异常会促进冠状动脉内皮功能受损、舒张功能障碍和缺血修复，这些都与肾小球超滤和近端小管钠和白蛋白处理功能受损同时发生。另一个重点是肥胖流行病在促进工业化国家心脏病和肾脏疾病发病率不断增加方面所起的作用，以及在促进成人和儿童心肾代谢综合征方面普遍存在的运动不足和过度消费廉价、不健康食品的问题。心肾医学面向多学科观众，包括肾病学家、心脏病学家、营养学家、内分泌学家、生理学家和一般内科医生。

The journal CardioRenal Medicine explores the mechanisms by which obesity and other metabolic abnormalities promote the pathogenesis and progression of heart and kidney disease (cardiorenal metabolic syndrome). It provides an interdisciplinary platform for the advancement of research and clinical practice, focussing on translational issues.Attention is paid to the fact that some metabolic abnormalities cluster with heart and chronic kidney disease, and collectively this is called the cardiorenal metabolic syndrome. Moreover, certain metabolic abnormalities of the heart promote impaired coronary artery endothelial function, diastolic dysfunction and ischemic reconditioning that parallel glomerular hyperfiltration and impairments in proximal tubule handling of sodium and albumin. Another point of focus is the role of the obesity epidemic in promoting the increasing incidence of heart and kidney disease in industrialized countries and the prevailing problems of insufficient exercise and excessive consumption of cheap, unwholesome food in promotion of the cardiorenal metabolic syndrome in both adults and children.CardioRenal Medicine addresses a multidisciplinary audience consisting of nephrologists, cardiologists, nutritionists, endocrinologists, physiologists and general internists.