Expert Review of Hematology

近年来，先进的分子研究技术已经改变了血液学。随着对血液病认识的提高，我们现在有机会研究和评估新的生物疗法、新药和药物组合、新的治疗计划和包括干细胞移植在内的新方法。我们还可以期待蛋白质组学、分子遗传学和生物标志物的研究能够促进新的诊断方法和合适的治疗方法的识别。随着我们对血细胞和造血组织的形成和功能的认识的进一步提高，对血液学家来说，采用这些新范式并制定综合策略来确定可能的最佳患者护理将是一个重大挑战。《血液学专家评论》(1747-4086)将这些进展纳入背景，并探讨如何将其直接转化为临床实践。领域包括:?急性白血病?贫血?出血失调?骨髓和造血干细胞移植?细胞疾病?慢性白血病?铁代谢紊乱?霍吉金斯疾病?血液学感染?免疫缺陷综合症?自身免疫性疾病?骨髓衰竭综合征?多发性骨髓瘤和淀粉样变性?嗜中性白血球减少症?非霍奇金淋巴瘤?儿科血液学?血小板疾病?血栓形成和止血?输血医学《血液学专家评论》提供评论和分析，阐明血液学的最佳临床实践，并将免疫学、干细胞研究、细胞和基因治疗等领域的研究进展转化为临床应用。

Advanced molecular research techniques have transformed hematology in recent years. With improved understanding of hematologic diseases, we now have the opportunity to research and evaluate new biological therapies, new drugs and drug combinations, new treatment schedules and novel approaches including stem cell transplantation. We can also expect proteomics, molecular genetics and biomarker research to facilitate new diagnostic approaches and the identification of appropriate therapies. Further advances in our knowledge regarding the formation and function of blood cells and blood-forming tissues should ensue, and it will be a major challenge for hematologists to adopt these new paradigms and develop integrated strategies to define the best possible patient care. Expert Review of Hematology (1747-4086) puts these advances in context and explores how they will translate directly into clinical practice. Areas covered include:? Acute leukemias ? Anemias ? Bleeding disorders ? Bone marrow and hematopoietic stem cell transplantation ? Cellular disorders ? Chronic leukemias ? Disorders of iron metabolism ? Hodgkins disease ? Infection in hematology ? Immunodeficiency syndromes ? Autoimmune diseases ? Marrow failure syndromes ? Multiple myeloma and amyloidosis ? Neutropenia ? Non-Hodgkin lymphomas ? Pediatric hematology ? Platelet disorders ? Thrombosis and hemostasis ? Transfusion medicine Expert Review of Hematology provides commentary and analysis to elucidate best clinical practice in hematology and to translate advances in research – in areas such as immunology, stem cell research, and cell and gene therapy – into the clinical context.