STRUCTURE

《结构》旨在发表在结构生物学领域具有特殊兴趣的论文。该杂志致力于成为结构生物学家，以及生物学家和生物化学家对大分子结构和功能感兴趣的基本读物。《结构》强烈鼓励提交关于生物功能和机制的结构和分子见解的手稿。其他涉及结构生物学基本问题的报告，例如蛋白质进化、折叠和/或设计的基于结构的检查，也将被优先考虑。我们将考虑任何方法的应用，实验或计算，在高或低分辨率，进行结构研究，只要该方法是适当的生物，功能和机械问题的解决。同样，描述单分子生物学机制分析的报告也很受欢迎。一般来说，编辑们鼓励提交结构研究，这些研究由处理结构-活动关系的额外实验系统进行验证，并且不会考虑只报告结构信息的研究，除非所调查的结构具有特殊和广泛的兴趣。

Structure aims to publish papers of exceptional interest in the field of structural biology. The journal strives to be essential reading for structural biologists, as well as biologists and biochemists that are interested in macromolecular structure and function. Structure strongly encourages the submission of manuscripts that present structural and molecular insights into biological function and mechanism. Other reports that address fundamental questions in structural biology, such as structure-based examinations of protein evolution, folding and/or design, will also be considered favorably. We will consider the application of any method, experimental or computational, at high or low resolution, to conduct structural investigations, as long as the method is appropriate for the biological, functional, and mechanistic question(s) being addressed. Likewise, reports describing single molecule analysis of biological mechanisms are welcome. In general, the editors encourage submission of structural studies that are validated by additional experimental systems that address structure-activity relationships, and will not consider studies that solely report structural information unless the structure under investigation is of exceptional and broad interest.