脂类化合物作为一类基本的生物化合物,其重要性已得到很好的证实。我们的生物化学、油脂化学和生理学知识在生物技术、油脂工业和医药领域的应用不断扩大。此外,还增加了新的领域,如脂质生物物理学,特别是与细胞膜和脂蛋白有关的,以及基本脂质体的研究和应用。为了应对知识领域的所有这些进步,需要一本期刊来回顾特定领域的最新进展,并将当前的研究置于其历史背景之下。脂质研究的进展实现了这一作用。每卷包含最新的调查,特别方面的脂质研究。这些审查是全面的,足以提供充分的概述,但集中于报告和批判性地评价最近的数据。选择这些科目是由于它们的及时性,或者因为最近几年发生了重大发展。它们包括方法学审查以及化学、生化和医学文章。所有脂类化合物和衍生物都包括在内,从脂肪酸和其他简单分子,到类固醇、萜类和磷脂或糖脂,再到复杂结构,如脂蛋白和生物膜。我们希望那些主要的兴趣在于脂质生物物理学和脂质体的研究将加入新的读者,受益于《华尔街日报》的经典脂质代谢、脂质信号转导和脂酶学,现在的读者将受益于暴露于高质量研究的新方面。
The importance of lipids as one of the fundamental classes of biological compounds is well established. The application of our knowledge of the biochemistry, chemistry and physiology of lipids to biotechnology, the fats and oils industry and medicine have continued to expand apace. In addition new dimensions such as lipid biophysics, especially with relevance to membranes and lipoproteins, and basic liposome research and applications have been added. To cope with all these advances in knowledge a journal is needed to review recent progress in particular fields and to set current research against its historical background. Progress in Lipid Research fulfils this role. Each volume contains up-to-date surveys of special aspects of lipid research. The reviews are comprehensive enough to provide sufficient overview but concentrate on reporting and critically appraising the most recent data. Subjects are chosen for their timeliness or because major developments have taken place in the last few years. They include methodological reviews as well as chemical, biochemical and medical articles. All lipid compounds and derivatives are covered, ranging from fatty acids and other simple molecules, through steroids, terpenoids and phospho- or glycolipids to complex structures such as lipoproteins and biological membranes. We hope that those whose main interest is in lipid biophysics and liposome research will join as new readers, benefiting from the journal's classical aspects of lipid metabolism, lipids in signal transduction and lipid enzymology, and that current readers will benefit from the exposure to top quality research on the new aspects.
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