突变研究综述的主题领域包括突变研究及其应用的整个科学领域,特别强调突变与疾病的关系。因此,本节将介绍人类基因组研究的进展(包括变异检测和功能基因组学的进化技术),以及在临床遗传学、基因治疗和相关环境因素健康风险评估中的应用。遗传毒理学和环境诱变(包括调节环境因子遗传活性的因子)将继续成为本节的重点。除了完整的评论外,还将发布关于特定主题的小评论。
The subject areas of Reviews in Mutation Researchencompass the entire spectrum of the science of mutation research and its applications, with particular emphasis on the relationship between mutation and disease. Thus this section will cover advances in human genome research (including evolving technologies for mutation detection and functional genomics) with applications in clinical genetics, gene therapy and health risk assessment for environmental agents of concern. Genetic toxicology and environmental mutagenesis (including the factors that modulate the genetic activity of environmental agents) will continue to be prominent topics in this section. In addition to full-length reviews, mini-reviews on specific topical themes will be published.
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