MOLECULAR AND BIOCHEMICAL PARASITOLOGY

该杂志为寄生虫原生动物和蠕虫的分子生物学和生物化学研究及其与最终宿主和中间宿主的相互作用的快速出版提供了一个媒介。所涵盖的主要范畴包括:?DNA、RNA、蛋白质、脂类、碳水化合物和小分子量物质的结构、生物合成、降解、性质和功能?中间代谢和生物能学?药物靶点表征及抗寄生虫药物的作用模式?膜结构和功能的分子和生化方面?寄主-寄主关系，主要关注寄主，特别是与特定的寄主分子相关的寄主-寄主关系。?基因和基因组结构、功能和表达分析?分析寄生虫种群中与基因交换、发病机制、药物和疫苗靶点表征以及耐药性相关的变异。?寄生虫蛋白的转运、细胞器的生物发生和细胞结构，特别是特定分子的作用?寄生虫在分子水平上对细胞的死亡、发育和分裂进行程序化处理只有当论文属于这些领域，如果它们包含有高科学质量的原创和完整的作品，并且呈现得很好，才会被接受发表。仅证实以前在其他生物体中研究过的基因的保守功能的论文将不予考虑。此外，以下工作领域更适合于其他期刊:?主要关注宿主反应的研究(如免疫学)?调查报告等位基因或应变频率在不同地区?在没有生物实验的硅模型或计算工作中?报告与生物学无关的等位基因或菌株频率的调查(例如，耐药性或发病机制)

The journal provides a medium for rapid publication of investigations of the molecular biology and biochemistry of parasitic protozoa and helminths and their interactions with both the definitive and intermediate host. The main subject areas covered are:? the structure, biosynthesis, degradation, properties and function of DNA, RNA, proteins, lipids, carbohydrates and small molecular-weight substances? intermediary metabolism and bioenergetics? drug target characterization and the mode of action of antiparasitic drugs? molecular and biochemical aspects of membrane structure and function? host-parasite relationships that focus on the parasite, particularly as related to specific parasite molecules.? analysis of genes and genome structure, function and expression? analysis of variation in parasite populations relevant to genetic exchange, pathogenesis, drug and vaccine target characterization, and drug resistance.? parasite protein trafficking, organelle biogenesis, and cellular structure especially with reference to the roles of specific molecules? parasite programmed cell death, development, and cell division at the molecular levelPapers will only be accepted for publication if they fall within these areas, if they contain original and complete work of high scientific quality, and if they are well presented. Papers solely confirming the conserved functions of genes previously studied in other organisms will not be considered.Additionally the following areas of work are better suited to other journals:? studies predominantly focused on the host response (e.g. immunology) ? surveys reporting allele or strain frequencies in various regions ? in silico modeling or computational work without biological experiments ? surveys reporting allele or strain frequencies not linked to biological relevance (e.g., drug resistance, or pathogenesis)