GENOMICS

基因组学是描述基因组规模技术的发展及其在生物研究各个领域的应用的论坛。《基因组学》是一本以其名字命名的期刊，它关注前沿方法的开发和应用，解决具有广泛受众潜在兴趣的基本问题。我们的目标是出版最高质量的研究报告，并为作者提供快速、公平和准确的审查和出版我们的范围内的手稿。基因组学范围内的主题包括但不限于:?基因组学包括基因组计划、基因组测序、基因组技术和新策略。?功能基因组学，包括转录谱分析、mRNA分析、microRNA分析，以及使用成熟的和新兴的技术(如数字基因表达)分析非编码和其他rna。?进化和比较基因组学，包括系统基因组学?基因组技术和方法学开发，重点关注在该领域和新兴技术中具有重大影响的令人兴奋的新应用?计算生物学、生物信息学和生物统计学，包括综合方法、网络生物学以及新工具和技术的开发?基因组规模的现代遗传学，包括复杂基因研究、群体基因组学、关联研究、结构变异和基因-环境相互作用?表观基因组学，包括DNA甲基化、组蛋白修饰、染色质结构、印迹和染色质重塑?基因组调控分析，包括DNA元素、基因座控制区域、绝缘体、增强子、沉默子和基因调控机制?理解疾病发病机制及其与遗传因素的关系的基因组学方法，包括元基因组、基因和基因组序列进化的模式和节奏。?医学基因组学、个人基因组学以及其他对人类健康的应用?基因组技术在模型生物中的应用可能会引起广泛的关注。?没有生物复制的RNA-seq实验将不被接受用于基于差异表达的文章。基因组学主要发表原创研究文章，但也欢迎对全文和微型评论的建议。所有提交给基因组学的论文都要经过严格的同行评审，我们的目标是只接受提交论文的前25-30%。请与编辑部联系，以审查建议或任何有关期刊的范围或适合出版的手稿的查询。

Genomics is a forum for describing the development of genome-scale technologies and their application to all areas of biological investigation.As a journal that has evolved with the field that carries its name, Genomics focuses on the development and application of cutting-edge methods, addressing fundamental questions with potential interest to a wide audience. Our aim is to publish the highest quality research and to provide authors with rapid, fair and accurate review and publication of manuscripts falling within our scope. Topics within the scope of Genomics include, but are not limited to:? Genomics including genome projects, genome sequencing, and genomic technologies and novel strategies.? Functional genomics including transcriptional profiling, mRNA analysis, microRNA analysis, and analysis of noncoding and other RNAs using established and newly-emerging technologies (such as digital gene expression).? Evolutionary and comparative genomics, including phylogenomics? Genomic technology and methodology development, with a focus on new and exciting applications with potential for significant impact in the field and emerging technologies? Computational biology, bioinformatics and biostatistics, including integrative methods, network biology, and the development of novel tools and techniques? Modern genetics on a genomic scale, including complex gene studies, population genomics, association studies, structural variation, and gene-environment interactions? Epigenomics, including DNA methylation, histone modification, chromatin structure, imprinting, and chromatin remodeling? Genomic regulatory analysis, including DNA elements, locus control regions, insulators, enhancers, silencers, and mechanisms of gene regulation? Genomic approaches to understanding the mechanism of disease pathogenesis and its relationship to genetic factors, including meta-genomic and the mode and tempo of gene and genome sequence evolution.? Medical Genomics, Personal Genomics, and other applications to human health? Application of Genomic techniques in model organisms that may be of interest to a wide audience.? RNA-seq experiments without biological replicates will not be accepted for differential expression–based articles.Genomics primarily publishes original research articles but also welcomes proposals for full-length and mini reviews. All submissions to Genomics are subject to rigorous peer review and our goal is to accept only the top 25-30% of submitted manuscripts. Please contact the Editorial Office with review proposals or any inquiries regarding the scope of the journal or the suitability of a manuscript for publication.