GENE

Gene拥有一个开放获取的镜像期刊Gene: X，目标和范围相同，编辑团队，投稿系统，严格的同行评审。Gene发表的论文关注于基因在所有生物环境中的调控、表达、功能和进化，包括所有原核生物、真核生物以及病毒。Gene致力于成为一个非常多样化的期刊，并将考虑出版各个领域的主题。虽然不限于下列各项，但一些一般性主题包括:?DNA组织、复制与进化-专注于基因组DNA(染色体组织、比较基因组学、DNA复制、DNA修复、移动DNA、线粒体DNA、叶绿体DNA)。?表达与功能-专注于功能rna (microRNAs, tRNAs, rRNAs, mRNA剪接，选择性聚腺苷酸化)?调节-专注于介导基因读出的过程(表观遗传学、染色质、组蛋白编码、转录、翻译、蛋白质降解)。?细胞信号-专注于控制信息流入细胞核以控制基因表达的机制(由细胞外配体、Wnt、Notch、TGFbeta/BMPs、FGFs、IGFs等控制的激酶和磷酸酶通路)。?基因表达和遗传变异的分析-专注于高通量方法(如DeepSeq、ChIP-Seq、Affymetrix微阵列、蛋白质组学)，这些方法定义了基因调控回路、分子通路和蛋白质/蛋白质网络。?遗传学——关注模型生物(如小鼠、青蛙、果蝇、蠕虫)、人类遗传变异、群体遗传学以及农业和兽医遗传学的发展。?分子病理学和再生医学-专注于人类疾病的分子过程的解除管制，以及通过多能或多能干细胞支持组织再生的机制。Gene鼓励提交具有合理分析水平、功能相关性和/或机械洞察力的小说手稿。Gene也欢迎那些主要具有描述性成分，但为后续功能研究改善了基本知识基础，或对最近发表的发现提供了重要证实的论文。验收的主要标准是作品的原创性和科学性。《华尔街日报》认识到，新颖性的标准是武断的，因学科和地理位置而异，也会随着时间而变化。该杂志将与编辑、评审和作者合作，促进论文的修订，以确保被接受的论文相对于同一领域内同时提交的论文来说是合理完整和有竞争力的。

Gene has an open access mirror journal Gene: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.Gene publishes papers that focus on the regulation, expression, function and evolution of genes in all biological contexts, including all prokaryotic and eukaryotic organisms, as well as viruses.Gene strives to be a very diverse journal and topics in all fields will be considered for publication. Although not limited to the following, some general topics include:? DNA Organization, Replication & Evolution -Focus on genomic DNA (chromosomal organization, comparative genomics, DNA replication, DNA repair, mobile DNA, mitochondrial DNA, chloroplast DNA).? Expression & Function - Focus on functional RNAs (microRNAs, tRNAs, rRNAs, mRNA splicing, alternative polyadenylation) ? Regulation - Focus on processes that mediate gene-read out (epigenetics, chromatin, histone code, transcription, translation, protein degradation). ? Cell Signaling - Focus on mechanisms that control information flow into the nucleus to control gene expression (kinase and phosphatase pathways controlled by extra-cellular ligands, Wnt, Notch, TGFbeta/BMPs, FGFs, IGFs etc.) ? Profiling of gene expression and genetic variation - Focus on high throughput approaches (e.g., DeepSeq, ChIP-Seq, Affymetrix microarrays, proteomics) that define gene regulatory circuitry, molecular pathways and protein/protein networks. ? Genetics - Focus on development in model organisms (e.g., mouse, frog, fruit fly, worm), human genetic variation, population genetics, as well as agricultural and veterinary genetics. ? Molecular Pathology & Regenerative Medicine - Focus on the deregulation of molecular processes in human diseases and mechanisms supporting regeneration of tissues through pluripotent or multipotent stem cells.Gene encourages submission of novel manuscripts that present a reasonable level of analysis, functional relevance and/or mechanistic insight. Gene also welcomes papers that have predominantly a descriptive component but improve the essential basis of knowledge for subsequent functional studies, or provide important confirmation of recently published discoveries.The primary criteria for acceptance are that the work is original and scientifically sound. The journal appreciates that standards of novelty are arbitrary, differ among disciplines and geographic locations, as well as change with time. In partnership with Editors, Referees and Authors, the journal will promote the revision of papers to ensure that accepted papers are reasonably complete and competitive with concurrent submissions in a given field.