剂量反应是一种开放获取的同行评议的在线期刊,发表有关剂量反应关系发生的原始发现和评论,涉及广泛的学科,包括生理学、生物化学、分子生物学、毒理学、放射生物学、药理学、药理学、医学、实验心理学、植物生物学以及环境和相关科学。特别感兴趣的是为非线性剂量-反应关系提供力学理解的实验证据。不在该杂志范围内的论文包括强调高剂量和两种少量(通常为3或更少)剂量的论文。目标受众探索基本适应机制的研究人员,以及对化学品、药品和辐射的风险评估感兴趣的研究人员。文章类型原创研究,特定主题的评论,简短的报告,临床案例,评论,以及给编辑的信件。感兴趣的话题U形剂量反应J型剂量反应非单调剂量响应非线性毒物兴奋效应/激效剂量反应两相的剂量反应前/后调节适应性反应
Dose-Response is an open access peer-reviewed online journal publishing original findings and commentaries on the occurrence of dose-response relationships across a broad range of disciplines, including physiology, biochemistry, molecular biology, toxicology, radiation biology, pharmacology, pharmacology, medicine, experimental psychology, plant biology, as well as environmental and related sciences. Particular interest focuses on experimental evidence providing mechanistic understanding of nonlinear dose-response relationships.Papers that are not within the scope of the journal include those that emphasize high doses and two few (typically 3 or less) doses.Target AudienceResearchers who explore fundamental adaptive mechanisms, as well as those interested in risk assessment of chemicals, pharmaceuticals, and radiation.Article TypesOriginal research, reviews on specific topics, short reports, clinical cases, commentaries, and letters to the editor.Topics of InterestU-shaped Dose ResponseJ-shaped Dose ResponseNon-monotonic Dose ResponseNon-linearityHormesis/Hormetic Dose ResponseBiphasic Dose ResponsePre/Post ConditioningAdaptive Response
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