CANCER AND METASTASIS REVIEWS

当代生物医学研究正处于一个时代的门槛，在这个时代，生理和病理过程可以用越来越精确和机械的术语来分析。生物学从一门以描述性为主的现象学学科，转变为一门可理解和可预测地操纵调控原则的学科，为癌症研究和寻找这种疾病的有效治疗方式带来了一个新的维度。癌症和转移综述为这些具有挑战性的进展提供了一个批判性综述和讨论的论坛。每一期的《癌症与转移评论》都有一个特定的主题或主题，并将包含5到7个不同的贡献。此外，一个介绍性前言包括从一个人谁是在该领域的杰出覆盖。主题和供稿人是由总编与编辑咨询委员会的不同成员协商后选定的。特别强调与癌症转移和肿瘤进展的分子和细胞生物学以及转移性疾病的治疗有关的主题。偶尔的问题将致力于对一种特定类型的癌症进行深入的临床和生物学分析。该杂志的一项主要功能是回顾生物学和恶性疾病治疗方面一些更重要和更有趣的最新进展，并强调新的和有希望的方向，无论是技术上还是概念上。我们鼓励投稿者回顾他们的个人作品，并进行猜测。

Contemporary biomedical research is on the threshold of an era in which physiological and pathological processes can be analyzed in increasingly precise and mechanistic terms. The transformation of biology from a largely descriptive phenomenological discipline to one in which the regulatory principles can be understood and manipulated with predictability brings a new dimension to the study of cancer and the search for effective therapeutic modalities for this disease. Cancer and Metastasis Reviews provides a forum for critical review and discussion of these challenging developments. Each issue of Cancer and Metastasis Reviews is devoted to a particular theme or topic and will contain from five to seven different contributions. In addition an introductory preface is included from an individual who is distinguished in the field to be covered. The topics and contributors are chosen by the Editor-in-Chief after consultation with various members of the Editorial Advisory Board. Special emphasis is placed on subjects which are of relevance to the molecular and cellular biology of cancer metastasis and tumor progression as well as to the treatment of metastatic disease. Occasional issues will be devoted to an in-depth clinical and biological analysis of a particular type of cancer. A major function of the journal is to review some of the more important and interesting recent developments in the biology and treatment of malignant disease as well as to highlight new and promising directions be they technological or conceptual. Contributors are encouraged to review their personal work and be speculative.