BIOCHEMICAL PHARMACOLOGY

《生物化学药理学》是一份国际期刊，出版的药理学研究成果来自于运用生物化学、生物物理学、分子生物学、遗传学、结构生物学、计算机模型和/或生理学等学科的调查。对完整的动物、器官、细胞、亚细胞成分、酶或其他细胞分子和模型系统的研究报告如果定义了药物作用的机制，是可以接受的。描述性数学模型包括那些涉及计算机技术的模型也受到欢迎。使用药物阐明生物体生理和行为机制的实验也在该杂志的范围内。一般来说，只有当药物和代谢产物在体液中的浓度有助于理解生物化学和生物物理机制时，才会被接受。但是，编辑保留发表该领域内任何重要论文的权利。只有英文稿件才会被考虑或发表。该杂志出版了以下类型的通讯(1)全文论文。这些工作包括提出与从事这项研究的调查人员提出的问题有关的原始调查结果。(2)短通信。这些作品包括范围较窄但质量相同的原创作品。根据定义，这些论文比完整的手稿短。(3)快速通信。这些促进了在《日刊》范围内迅速传播及时和重要的意见。稿件必须以英文提交，并将根据其当前的重要性，作为快速通讯的依据，判断是否适合出版。他们应该写清楚地强调研究的新颖方面。这些标准将严格执行。(4)评注是委托评审的短文(长度在3000-5000字之间)。它们被设计成对选定主题的编辑声明，而不应是详尽的评论。评论主要是为了激发思考。它们可能是有争议的，既可以集中在活动较多的领域，也可以将注意力吸引到相对被忽视的领域，在这些领域中有机会也有必要进行生化药理学的研究。特别值得欢迎的是，作者将在评论中就他们所报道的主题的状况提出他们个人的看法，并就该主题在不久或遥远的将来可能会走向何方提出他们的看法。特别鼓励作家们对流行的教条提出异议。

Biochemical Pharmacology is an international journal which publishes research findings in pharmacology deriving from investigations that employ the disciplines of biochemistry, biophysics, molecular biology, genetics, structural biology, computer models and/or physiology. Reports of studies with intact animals, organs, cells, subcellular components, enzymes or other cellular molecules and model systems are acceptable if they define mechanisms of drug action. Descriptive mathematical models including those involving computer techniques are also welcome. Experiments involving the use of drugs to elucidate physiological and behavioral mechanisms in living organisms are also within the scope of the journal. In general, papers that record concentrations of drugs and metabolites in body fluids will only be accepted if they contribute to an understanding of biochemical and biophysical mechanisms. The Editors, however, reserve the right to publish any papers of major interest in the field. Only contributions in English will be considered or published. The journal publishes the following types of communications (1) Full-length Papers. These consist of a body of work presenting original findings relating to the question proposed by the investigators undertaking the research. (2) Short Communications. These consist of an original body of work of narrower scope but of the same quality as the above. By definition, these papers are shorter than full-length manuscripts. (3) Rapid Communications. These promote rapid dissemination of timely and significant observations within the scope of the journal. Manuscripts must be submitted in English and will be judged as appropriate for publication as rapid communications on the basis of their immediate importance. They should be written to emphasize clearly the novel aspects of the research. These criteria will be applied strictly. (4) Commentaries are short commissioned review articles (3000-5000 words in length). They are designed to be editorial statements on selected topics, and should not be exhaustive reviews. Primarily, Commentaries are intended to stimulate thought. They can be controversial, and can either focus on areas subject to much activity, or draw attention to relatively neglected fields in which there is both the opportunity and the need for research in biochemical pharmacology. Particularly welcome will be Commentaries in which authors present their personal view on the state of the subject on which they are reporting, and give their view as to where in the near or distant future the subject may be moving. Authors are especially encouraged to take issue with popular dogmas.